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polyclonal goat anti cxcl16 antibody  (R&D Systems)


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    R&D Systems polyclonal goat anti cxcl16 antibody
    Polyclonal Goat Anti Cxcl16 Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 22 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/polyclonal goat anti cxcl16 antibody/product/R&D Systems
    Average 94 stars, based on 22 article reviews
    polyclonal goat anti cxcl16 antibody - by Bioz Stars, 2026-03
    94/100 stars

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    Immunohistochemistry was used to detect the expression of <t>CXCL16</t> and CXCR6 in tissue sections. Sections of invasive SCC, CIN3, CIN2, and normal cervix were stained for CXCL16 and CXCR6 (×200). Both CXCL16 and CXCR6 antigens are expressed in the epithelia and stroma of neoplastic squamous and glandular lesions. The epithelial staining is clearly intracellular and well defined, whereas stromal staining is generally diffuse and weak. CXCL16 and CXCR6 exhibit strong expression in the cytoplasm and membrane throughout the full thickness of the epithelium in SCC and CIN3. In contrast, CXCL16 or CXCR6 staining is decreased and confined to the basal layers of the epithelia in CIN2 lesions. The normal ectocervix shows weak staining for CXCL16 in epithelia and stroma but is consistently negative for CXCR6.
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    Immunohistochemistry was used to detect the expression of <t>CXCL16</t> and CXCR6 in tissue sections. Sections of invasive SCC, CIN3, CIN2, and normal cervix were stained for CXCL16 and CXCR6 (×200). Both CXCL16 and CXCR6 antigens are expressed in the epithelia and stroma of neoplastic squamous and glandular lesions. The epithelial staining is clearly intracellular and well defined, whereas stromal staining is generally diffuse and weak. CXCL16 and CXCR6 exhibit strong expression in the cytoplasm and membrane throughout the full thickness of the epithelium in SCC and CIN3. In contrast, CXCL16 or CXCR6 staining is decreased and confined to the basal layers of the epithelia in CIN2 lesions. The normal ectocervix shows weak staining for CXCL16 in epithelia and stroma but is consistently negative for CXCR6.
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    Average 94 stars, based on 1 article reviews
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    94/100 stars
    		  Buy from Supplier

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    Immunohistochemistry was used to detect the expression of CXCL16 and CXCR6 in tissue sections. Sections of invasive SCC, CIN3, CIN2, and normal cervix were stained for CXCL16 and CXCR6 (×200). Both CXCL16 and CXCR6 antigens are expressed in the epithelia and stroma of neoplastic squamous and glandular lesions. The epithelial staining is clearly intracellular and well defined, whereas stromal staining is generally diffuse and weak. CXCL16 and CXCR6 exhibit strong expression in the cytoplasm and membrane throughout the full thickness of the epithelium in SCC and CIN3. In contrast, CXCL16 or CXCR6 staining is decreased and confined to the basal layers of the epithelia in CIN2 lesions. The normal ectocervix shows weak staining for CXCL16 in epithelia and stroma but is consistently negative for CXCR6.

    Journal: Chinese Journal of Cancer

    Article Title: Expression of the CXCL12/CXCR4 and CXCL16/CXCR6 axes in cervical intraepithelial neoplasia and cervical cancer

    doi: 10.5732/cjc.012.10063

    Figure Lengend Snippet: Immunohistochemistry was used to detect the expression of CXCL16 and CXCR6 in tissue sections. Sections of invasive SCC, CIN3, CIN2, and normal cervix were stained for CXCL16 and CXCR6 (×200). Both CXCL16 and CXCR6 antigens are expressed in the epithelia and stroma of neoplastic squamous and glandular lesions. The epithelial staining is clearly intracellular and well defined, whereas stromal staining is generally diffuse and weak. CXCL16 and CXCR6 exhibit strong expression in the cytoplasm and membrane throughout the full thickness of the epithelium in SCC and CIN3. In contrast, CXCL16 or CXCR6 staining is decreased and confined to the basal layers of the epithelia in CIN2 lesions. The normal ectocervix shows weak staining for CXCL16 in epithelia and stroma but is consistently negative for CXCR6.

    Article Snippet: After blocking with 7% horse normal serum for 30 min at room temperature, sections were incubated with mouse monoclonal anti-CXCL12 (R&D, dilution 1:25), mouse monoclonal anti-CXCR4 (R&D, dilution 1:80), goat polyclonal anti-CXCL16 (R&D, dilution 1:10), or mouse monoclonal anti-CXCR6 (R&D, dilution 1:40) overnight at 4°C.

    Techniques: Immunohistochemistry, Expressing, Staining

    Correlation among CXCL12, CXCR4, CXCL16, and CXCR6

    Journal: Chinese Journal of Cancer

    Article Title: Expression of the CXCL12/CXCR4 and CXCL16/CXCR6 axes in cervical intraepithelial neoplasia and cervical cancer

    doi: 10.5732/cjc.012.10063

    Figure Lengend Snippet: Correlation among CXCL12, CXCR4, CXCL16, and CXCR6

    Article Snippet: After blocking with 7% horse normal serum for 30 min at room temperature, sections were incubated with mouse monoclonal anti-CXCL12 (R&D, dilution 1:25), mouse monoclonal anti-CXCR4 (R&D, dilution 1:80), goat polyclonal anti-CXCL16 (R&D, dilution 1:10), or mouse monoclonal anti-CXCR6 (R&D, dilution 1:40) overnight at 4°C.

    Techniques:

    Association of CXCL12, CXCR4, CXCL16, or CXCR6 with clinicopathologic features

    Journal: Chinese Journal of Cancer

    Article Title: Expression of the CXCL12/CXCR4 and CXCL16/CXCR6 axes in cervical intraepithelial neoplasia and cervical cancer

    doi: 10.5732/cjc.012.10063

    Figure Lengend Snippet: Association of CXCL12, CXCR4, CXCL16, or CXCR6 with clinicopathologic features

    Article Snippet: After blocking with 7% horse normal serum for 30 min at room temperature, sections were incubated with mouse monoclonal anti-CXCL12 (R&D, dilution 1:25), mouse monoclonal anti-CXCR4 (R&D, dilution 1:80), goat polyclonal anti-CXCL16 (R&D, dilution 1:10), or mouse monoclonal anti-CXCR6 (R&D, dilution 1:40) overnight at 4°C.

    Techniques:

    Arrays containing cervical cancer tissue from 103 patients were stained for CXCL12, CXCR4, CXCL16, and CXCR6, and samples were scored for their expression as described in the Materials and Methods section. Samples were grouped according to stage as determined by the supplier, and mean scores for protein expression were calculated. The number of samples ( n ) in each stage group is shown. Stage 0 includes 43 cases of CIN3. Error bars show standard errors of measurement. Cross bars indicate comparisons that are significant. * P < 0.05; *** P < 0.001.

    Journal: Chinese Journal of Cancer

    Article Title: Expression of the CXCL12/CXCR4 and CXCL16/CXCR6 axes in cervical intraepithelial neoplasia and cervical cancer

    doi: 10.5732/cjc.012.10063

    Figure Lengend Snippet: Arrays containing cervical cancer tissue from 103 patients were stained for CXCL12, CXCR4, CXCL16, and CXCR6, and samples were scored for their expression as described in the Materials and Methods section. Samples were grouped according to stage as determined by the supplier, and mean scores for protein expression were calculated. The number of samples ( n ) in each stage group is shown. Stage 0 includes 43 cases of CIN3. Error bars show standard errors of measurement. Cross bars indicate comparisons that are significant. * P < 0.05; *** P < 0.001.

    Article Snippet: After blocking with 7% horse normal serum for 30 min at room temperature, sections were incubated with mouse monoclonal anti-CXCL12 (R&D, dilution 1:25), mouse monoclonal anti-CXCR4 (R&D, dilution 1:80), goat polyclonal anti-CXCL16 (R&D, dilution 1:10), or mouse monoclonal anti-CXCR6 (R&D, dilution 1:40) overnight at 4°C.

    Techniques: Staining, Expressing

    The overall survival of cervical cancer patients was plotted by using Kaplan-Meier estimates according to low the expression level of CXCL12 (A), CXCR4 (B), CXCL16 (C), and CXCR6 (D). Low protein expression is identified with a staining index of 0–3; high protein expression is identified with a staining index of 4–6. Curves were compared using the log-rank test. Among all proteins, only CXCR6 expression had any impact on overall survival. In this group, overall survival rate was significantly lower in patients whose tumors expressed high levels of CXCR6 than in patients whose tumors expressed low levels of CXCR6.

    Journal: Chinese Journal of Cancer

    Article Title: Expression of the CXCL12/CXCR4 and CXCL16/CXCR6 axes in cervical intraepithelial neoplasia and cervical cancer

    doi: 10.5732/cjc.012.10063

    Figure Lengend Snippet: The overall survival of cervical cancer patients was plotted by using Kaplan-Meier estimates according to low the expression level of CXCL12 (A), CXCR4 (B), CXCL16 (C), and CXCR6 (D). Low protein expression is identified with a staining index of 0–3; high protein expression is identified with a staining index of 4–6. Curves were compared using the log-rank test. Among all proteins, only CXCR6 expression had any impact on overall survival. In this group, overall survival rate was significantly lower in patients whose tumors expressed high levels of CXCR6 than in patients whose tumors expressed low levels of CXCR6.

    Article Snippet: After blocking with 7% horse normal serum for 30 min at room temperature, sections were incubated with mouse monoclonal anti-CXCL12 (R&D, dilution 1:25), mouse monoclonal anti-CXCR4 (R&D, dilution 1:80), goat polyclonal anti-CXCL16 (R&D, dilution 1:10), or mouse monoclonal anti-CXCR6 (R&D, dilution 1:40) overnight at 4°C.

    Techniques: Expressing, Staining